4/30/2023 0 Comments Spaceclaim 2020![]() ![]() The purpose of this research was to investigate the effects of the following potential confounding factors on LAA t m and C ∞: (1) pulmonary vein flow waveform pulsatility, (2) non-Newtonian blood rheology and hematocrit level, and (3) length of the simulation. We showed in our previous study that residence time distribution (RTD) of blood-borne particles in the LAA and its associated calculated variables (i.e., mean residence time, t m, and asymptotic concentration, C ∞) have the potential to improve CHA 2DS 2-VASc score. The conventional metric of stroke risk stratification, CHA 2DS 2-VASc score, does not account for LAA morphology or hemodynamics. 5Heart and Vascular Institute, UPMC Presbyterian, Pittsburgh, PA, United Statesīackground: Atrial fibrillation (AF) is a prevalent arrhythmia, that causes thrombus formation, ordinarily in the left atrial appendage (LAA).4Cardiovascular Research Institute Maastricht (CARIM), Department of Cardiology, Maastricht University Medical Center, Maastricht, Netherlands. ![]() 3Heart Center, Department of Electrophysiology, University of Leipzig, Leipzig, Germany.2Department of Electrophysiology, Massachusetts General Hospital, Boston, MA, United States.1Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States.Soroosh Sanatkhani 1, Sotirios Nedios 2,3,4, Prahlad G. ![]()
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